BrAIST: planning and current status of Bracing in Adolescent Idiopathic Scoliosis Trial
نویسندگان
چکیده
The randomized controlled trial has emerged as the gold standard for all clinical research. The combination of randomized assignment to groups, use of strict inclusion and exclusion criteria, standardized protocols and ad hoc power analysis serve to rule out many threats to the internal validity of research results. Thus, it is the most powerful methodology available to researchers investigating the relative effectiveness of treatments.
منابع مشابه
To BrAIST or not to BrAIST: decisions and characteristics of 1131 patients eligible for the Bracing in Adolescent Idiopathic Scoliosis Trial
Background BrAIST is a partially-randomized trial comparing the outcomes of bracing and observation in children with adolescent idiopathic scoliosis. The purpose of this study is to evaluate 1) whether the BrAIST sample is representative of the target population and 2) whether the treatment arms are equivalent. We addressed these questions by comparing baseline demographic, radiographic and psy...
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Background A recently published NIH-funded study named “Bracing in Adolescent Idiopathic Scoliosis Trial” (BrAIST) affirmed the efficacy of bracing for moderate adolescent idiopathic scoliosis (AIS) and reduced surgical recommendations in braced patients. The implications of this study are numerous. BrAIST affirms the value of bracing, but also confirms the importance of wear time, and points t...
متن کاملEvaluation of TLSOS in the bracing in adolescent idiopathic scoliosis trial (BrAIST)
Background The success of TLSOs in reducing the risk of curve progression varies widely across published reports. This variation has been linked to patient risk factors such as initial Cobb angle and maturity, and time in brace. Percentage correction has also been associated with outcomes. [1-3] However, no reports have examined characteristics of individual braces, and how these characteristic...
متن کاملBody Image and Quality of Life and Brace Wear Adherence in Females With Adolescent Idiopathic Scoliosis
BACKGROUND Clinical evidence regarding the ability of braces to decrease the risk of curve progression to surgical threshold in patients with adolescent idiopathic scoliosis (AIS) continues to strengthen. Unfortunately, there is still a great deal of uncertainty regarding the impact of brace wear on psychosocial well-being or the impact of psychological well-being on brace wear adherence. The p...
متن کاملEffects of bracing in adolescents with idiopathic scoliosis.
BACKGROUND The role of bracing in patients with adolescent idiopathic scoliosis who are at risk for curve progression and eventual surgery is controversial. METHODS We conducted a multicenter study that included patients with typical indications for bracing due to their age, skeletal immaturity, and degree of scoliosis. Both a randomized cohort and a preference cohort were enrolled. Of 242 pa...
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